Lintlha tse 'maloa tse kholo tse amang ho bolokoa ha Metsi a Hydroxypropyl Methylcellulose
Hydroxypropyl Methylcellulose (HPMC) ke polymer e sebelisoang haholo liindastering tse fapaneng, ho kenyeletsoa kaho, meriana, lijo le tlhokomelo ea motho.E 'ngoe ea thepa ea eona ea bohlokoa ke ho boloka metsi, e bolelang bokhoni ba HPMC ba ho boloka metsi ka har'a motsoako kapa thepa.Ho boloka metsi ho bohlokoa lits'ebetsong moo taolo ea mongobo, viscosity le botsitso li hlokahalang.Sehloohong sena, re tla hlahloba lintlha tse 'maloa tse kholo tse amang ho bolokoa ha metsi ha HPMC le ho buisana ka bohlokoa ba tsona liindastering tse fapaneng.Ho utloisisa lintlha tsena ho ka thusa bafuputsi le bahlahisi ho ntlafatsa litlolo le ho ntlafatsa ts'ebetso ea lihlahisoa tse thehiloeng ho HPMC.
Boima ba Molek'hule ea HPMC
Boima ba limolek'hule tsa HPMC ke ntlha ea bohlokoa e susumetsang matla a eona a ho boloka metsi.Li-polymers tse phahameng tsa HPMC li na le matla a ho ts'oara metsi a mangata ha li bapisoa le boima bo tlase ba limolek'hule.Sena ke hobane boima bo phahameng ba limolek'hule HPMC e na le liketane tse telele tsa polymer, tse fanang ka libaka tse ngata bakeng sa limolek'hule tsa metsi ho sebelisana le ho theha li-bond tsa hydrogen.Ka lebaka leo, liketane tse nang le hydrated polymer lia ruruha 'me li boloka metsi ka katleho.Baetsi ba ka khetha boima ba molek'hule bo loketseng ba HPMC ho ipapisitsoe le thepa e lakatsehang ea ho boloka metsi bakeng sa lits'ebetso tse ikhethileng.
Degree of Substitution (DS)
Tekanyo ea phapanyetso e bolela boholo ba hydroxypropyl le methoxy substitution ho mokokotlo oa cellulose oa HPMC.E susumetsa haholo litšobotsi tsa ho boloka metsi tsa HPMC.Ka kakaretso, boleng bo phahameng ba DS bo lebisa mekhoeng e ntlafalitsoeng ea ho boloka metsi.Lihlopha tsa hydroxypropyl le methoxy li eketsa hydrophilicity ea polymer, e lumellang ho monya le ho boloka metsi a mangata.Boleng ba DS bo ka fetoloa nakong ea ho qaptjoa ha HPMC ho fihlela thepa e lakatsehang ea ho boloka metsi bakeng sa lits'ebetso tse fapaneng.
Tsepamiso ea maikutlo ea HPMC ho Tlhahiso
Khatello ea HPMC ha e etsoa e ama ka kotloloho bokhoni ba eona ba ho boloka metsi.Ha mahloriso a HPMC a ntse a eketseha, ho na le keketseho e lekanang ea ho boloka metsi.Sena se bakoa ke hore bongata bo phahameng ba HPMC bo fana ka libaka tse ngata tse tlamang tsa limolek'hule tsa metsi, tse lebisang ho ntlafatseng ha metsi le matla a ho boloka metsi.Leha ho le joalo, ho bohlokoa ho ela hloko hore khatello e phahameng haholo ea HPMC e ka baka ho eketseha ha viscosity kapa sebopeho sa gel, se ka amang hampe ts'ebeliso le ts'ebetso ea sebopeho.
Mocheso le Mongobo
Mocheso le mongobo ke lintlha tsa kantle tsa tikoloho tse ka susumetsang thepa ea ho boloka metsi ea liforomo tse thehiloeng ho HPMC.Lithempereichara tse phahameng li atisa ho potlakisa ho fetoha mouoane ha metsi ho tsoa ho sebopeho, ho fokotsa ho boloka metsi.Ka lehlakoreng le leng, lithempereichara tse tlase li ka khothaletsa ho bolokoa ha metsi ka ho liehisa tšebetso ea mouoane.Maemo a mongobo le ona a phetha karolo, kaha mongobo o phahameng o ka thusa ho boloka mongobo ka har'a motsoako, ho matlafatsa ho boloka metsi.Ho bohlokoa ho nahana ka maemo a ts'ebetso le maemo a tikoloho ha ho etsoa meralo ea HPMC ho netefatsa ts'ebetso e nepahetseng ea ho boloka metsi.
Likamano le lisebelisoa tse ling
Ho ba teng ha metsoako e meng ha ho etsoa ho ka ama haholo thepa ea ho boloka metsi ea HPMC.Litšebelisano tse kopanetsoeng kapa tse hanyetsanang li ka etsahala pakeng tsa HPMC le li-additives tse ling, tse amang matla a ho tšoara metsi ka kakaretso.Ka mohlala, matsoai a itseng kapa li-ion tse teng ha ho etsoa li ka qothisana lehlokoa le HPMC bakeng sa limolek'hule tsa metsi, ho fokotsa bokhoni ba eona ba ho boloka metsi.Ka lehlakoreng le leng, ho kenyelletsa li-additives tse bolokang metsi, joalo ka li-humectants kapa polyols, li ka ntlafatsa bokhoni ba ho ts'oara metsi ba HPMC.Ho utloisisa tšebelisano le tšebelisano lipakeng tsa HPMC le lisebelisoa tse ling ho bohlokoa bakeng sa ho theha litsamaiso tse sebetsang tse nang le thepa e nepahetseng ea ho boloka metsi.
